Recombinant Human Galectin 9/LGALS9 Protein (His Tag)(Active)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032470-10, PKSH032470-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Galectin 9; LGALS9

Target Symptom: Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9

Target Species: Human

Expression Host: HEK293 Cells

Application: ELISA

Fusion Tag: C-6His

UNIProt ID: Q3B8N1

Accession: Q3B8N1-2

Background: Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.

Activity: Immobilized Human Galectin 9-His at 10μg/ml(100 μl/well) can bind Cynomolgus TIM-3-His(Cat: PKSQ050023). The ED50 of Human Galectin 9-His is 1.75 ug/ml.

Sequence: Met 1-Thr323

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, 1mM EDTA, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 36.9 kDa

Observed MW: 49 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only